A new partnership between the American College of Cardiology and OpenEvidence will integrate generative AI into cardiovascular workflows, empowering clinicians with rapid, evidence-based insights to deliver smarter, safer, and more personalized care for the heart.

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The American College of Cardiology (ACC) and OpenEvidence are entering a strategic partnership to accelerate the translation of cardiovascular clinical guidance and research into clinical implementation at the point of care. By combining ACC's leadership in cardiovascular science and education with OpenEvidence's advanced generative artificial intelligence (AI) technology, clinicians will have access to the latest relevant and actionable medical evidence to support shared decision-making with their patients.
Integrating responsible AI into cardiovascular workflows
"At the American College of Cardiology, our mission is to transform cardiovascular care and improve heart care for all because patients deserve care that's not only informed by the latest scientific evidence, but also delivered with confidence and compassion," said ACC Chief Executive Officer Cathleen C. Gates. "Our collaboration with OpenEvidence will allow us to responsibly integrate AI into clinical workflows, ensuring that patients benefit from timely, evidence-based care without compromising safety, transparency or the trusted judgment of their clinicians."
Enhancing clinical decision-making through AI-powered evidence access
Through this partnership, OpenEvidence users will benefit from seamless access to trusted, evidence-based medical content curated by the ACC. By integrating generative AI-powered search capabilities, the platform enhances the clinical decision-making experience at the point of care with both speed and accuracy.
OpenEvidence underscores the central role of cardiovascular care
"When we look at what clinicians are searching on OpenEvidence, the heart is everywhere: central to pathophysiology, and central to clinical decision-making," said Daniel Nadler, PhD, CEO of OpenEvidence. "From family physicians and emergency doctors to intensivists and trauma surgeons, clinicians across every specialty rely on the work of the ACC to guide evidence-based care. We're thrilled to partner with the organization that defines the foundation for cardiovascular practice, bringing their trusted expertise to the point of care through responsible, generative AI."
Expert work group to guide evidence-based implementation
The creation of supplemental materials to support evidence-based treatment and care delivery is a major aspect of the collaboration. The ACC and OpenEvidence will convene an expert workgroup of cardiovascular clinicians to identify high-impact areas, frequently asked questions, and assess knowledge gaps based on the questions clinicians ask at the point of care. The work group will also explore opportunities to enhance the development of clinical guidance and the creation of new educational materials to optimize the use of generative AI in practice.
Future initiatives: AI resource center and educational outreach
An ACC/OpenEvidence AI Resource Center and a podcast series are also in development, exploring how AI technologies are shaping cardiovascular medicine. Additionally, the College will partner with OpenEvidence on the ACC Future Hub at the ACC Annual Scientific Session, providing attendees with frontline access to practice-changing technologies that can be used to optimize patient care and outcomes.